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The Top Weight Loss.com

trimrx vs wellmedr: Custom Dosing or the Lowest Price Per Month?

A hands-on, custom-dosed program against the cheapest ongoing GLP-1 price we track

By The Top Weight Loss Editorial Team·

Last updated: Oct 3, 2026

Francheska Capistrano, Medical Content Reviewer

Reviewed for medical accuracy by Francheska Capistrano, RMT, MPH

Reviewed · How we review

We may earn a commission from links on this page - it never affects our rankings (how we stay objective).

The verdict

wellmedr is the stronger pick for most people - $49/mo semaglutide on the 12-month plan. Full reasoning, pricing and the cases where trimrx wins are below.

At a glancetrimrxwellmedr
Starting price$149/mo$49/mo on 12-month plan
MedicationsCompounded sema & tirz + brandedCompounded sema & tirz + brand-name
PrescriptionRequired - online provider reviewRequired - online provider review
DeliveryFree, often next-day3-5 business days

Prices are the providers’ published rates at our last verification - confirm the final figure at checkout, as offers change. How we verify prices

trimrx logo
5,393 reviews onTrustpilot
Licensed US telehealth

Custom-dosed compounded GLP-1s with unlimited provider check-ins and fast, free tracked delivery

  • Semaglutide $149/mo at every dose
  • Custom dosing by your provider
  • Unlimited provider check-ins
Visit trimrx
VS
wellmedr logo
2,181 reviews onTrustpilot
Licensed US telehealth

The lowest long-run compounded GLP-1 price we found - semaglutide from $49/mo on a 12-month plan

  • Semaglutide $49/mo (12-month plan)
  • Tirzepatide $89/mo, same price every dose
  • Board-certified clinicians
Visit wellmedr

The full breakdown

trimrx vs wellmedr: a closer look at each

Both are credible providers in this category, and the right pick comes down to fit. So instead of crowning a “winner,” here’s the real rundown on each - what you get, what it actually costs, and what real customers are saying - so you can pick the one that fits you.

trimrx logo
5,393 reviews onTrustpilot
Licensed US telehealth
Visit trimrx

What is trimrx?

trimrx is aimed at people who want more control over their dose and more contact with a provider. Instead of a fixed titration schedule, its providers offer custom dosing - including smaller step-ups for people who struggle with side effects - and you get unlimited provider check-ins to adjust along the way.

Read the full trimrx breakdown▾

Getting started is simple: an asynchronous questionnaire, no appointment needed. Delivery is free and tracked, often next-day, and plans are month-to-month.

The trade-offs are price (it sits at the higher end of compounded programs) and a program that is light on lifestyle coaching. As with every compounded program, the medication is not FDA-approved.

This review covers what trimrx costs and who it suits.

Custom dosingUnlimited check-insOften next-day delivery

What you get with trimrx

  • Compounded semaglutide $149/month at every dose; tirzepatide $259/month
  • Custom dosing tailored by your provider
  • Unlimited provider check-ins
  • Async questionnaire - no appointment needed
  • Delivery often next-day
  • Month-to-month, no commitment; HSA/FSA eligible

Who trimrx is best for

  • People who want custom or micro dosing to manage side effects
  • Anyone who values frequent provider touchpoints
  • Those who want fast delivery without a long commitment
  • Skip it if price is your priority - embody and wellmedr cost considerably less

How much does trimrx cost?

trimrx charges $149/month for compounded semaglutide at every dose (with a $140 discount applied) and $259/month for compounded tirzepatide.

Full pricing details▾

Branded options are also available at much higher prices. Plans are month-to-month with no commitment, delivery is free and tracked, and HSA/FSA funds can be used.

The discount is promotional, so confirm the current price at checkout. Compounded GLP-1s are not FDA-approved.

Semaglutide

Compounded semaglutide

$149/mo

Month-to-month, same price at every dose

  • $140 discount applied
  • Custom dosing
  • Unlimited provider check-ins

Tirzepatide

Compounded tirzepatide

$259/mo

Month-to-month, no commitment

  • Custom dosing
  • Free tracked delivery
  • HSA/FSA eligible

What we like about trimrx

  • Custom dosing - useful if standard step-ups cause side effects
  • Unlimited provider check-ins at no extra cost
  • Fast, free tracked delivery - often next-day
  • No appointment needed, month-to-month and HSA/FSA eligible

Worth keeping in mind

  • Higher price than embody, altRx's promo or wellmedr - $149 semaglutide and $259 tirzepatide
  • Compounded medication is not FDA-approved or FDA-reviewed for safety, effectiveness or quality
  • Light on coaching - little nutrition or lifestyle support
  • Mixed Trustpilot rating (3.8 / 5 from 5,393 reviews); available in most, not all, US states

What real trimrx customers are saying

trimrx logo

trimrx reviews on

Trustpilot
(5,393 reviews)
Oct 10, 2026

Signup was easy and the price beat a...

“Signup was easy and the price beat a few places I checked, my medication hasn't arrived yet. For now I can only rate the ordering part.”

T

Tiffany Luwe

US

Oct 10, 2026

Down 14 lbs so far and my appetite has...

“Down 14 lbs so far and my appetite has dropped a lot”

S

Susan Kovi

US

Oct 10, 2026

Approved the same day and had the...

“Approved the same day and had the medication two days later really quick process from start to finish.”

V

Vickie Shelton

US

Oct 11, 2026

I got prompt answers to my concerns

“I got prompt answers to my concerns, and shipping was fast.”

N

Najera Bennett

US

Oct 11, 2026

For the past few months

“For the past few months, my medication has arrived on time ,I have been happy with the care and service too.”

C

Courtney Gruppen

US

Oct 10, 2026

No problems getting my GLP 1 order...

“No problems getting my GLP 1 order through the website.”

L

Leemurphy Nino

US

Oct 10, 2026

My insurance denied ozempic again

“My insurance denied ozempic again, so with my endocrinologist on board I decided to try compounded semaglutide through trimrx. I've been on it since August and my A1C has gone from 7.2 to 6.5, plus I've been losing weight. My doctor was really happy with the change and getting started with trimrx was pretty straightforward.”

L

Leslie

US

Oct 10, 2026

I'm on 0.5mg semaglutide and only had a...

“I'm on 0.5mg semaglutide and only had a bit of nausea the first week, the biggest surprise has been having more energy and sleeping better too.”

L

Loretta Rigsby

US

Oct 10, 2026

The medication has been working well...

“The medication has been working well for me and deliveries have always shown up on time. My only issue is that I had to follow up twice before getting an answer about my dose, so I'm sticking with 4 stars for now.”

E

Elnora Watkins

US

Oct 10, 2026

Meds have been working well and...

“Meds have been working well and deliveries have always been on time.”

R

Robert Vaughn

US

Oct 10, 2026

6 weeks in and I'm down 15 lbs on...

“6 weeks in and I'm down 15 lbs on semaglutide”

R

Ronald Franzer

US

Get started with trimrx
wellmedr logo
2,181 reviews onTrustpilot
Licensed US telehealth
Visit wellmedr

What is wellmedr?

wellmedr is a broad telehealth platform - it also covers TRT, NAD+, hair and sexual health - with a GLP-1 program priced to win on long-term cost. Its headline rate is compounded semaglutide at $49/month, but that price is locked in only on a 12-month plan; month-to-month is advertised at around $88/month.

Read the full wellmedr breakdown▾

Compounded tirzepatide is $89/month, shipped every 4 weeks, and both are the same price at every dose. Board-certified clinicians review your intake, with video or messaging follow-up, and it is available in all 50 states.

It also has the strongest Trustpilot score of the providers we rank that publish one. As with every compounded program, these medications are not FDA-approved.

This review covers what wellmedr costs, what the 12-month plan means for you, and who it suits.

Board-certified cliniciansAll 50 statesSame price at every dose

What you get with wellmedr

  • Compounded semaglutide $49/month on a 12-month plan (rate locked)
  • Compounded tirzepatide $89/month, shipped every 4 weeks
  • Same price at every dose
  • Board-certified clinicians; async intake plus video or messaging
  • GLP-1 + NAD+/B12 microdose option; brand-name shelf
  • Available in all 50 states; ships in 3-5 business days

Who wellmedr is best for

  • People confident they will stay on a GLP-1 for a year and want the lowest total cost
  • Anyone who wants tirzepatide at a low flat price
  • Those in states other providers do not serve
  • Skip it if you want flexibility to stop in a month or two - embody is cheaper month-to-month

How much does wellmedr cost?

wellmedr's compounded semaglutide is $49/month on its 12-month plan, with the rate locked for the year; month-to-month is higher, advertised at around $88/month.

Full pricing details▾

Compounded tirzepatide is $89/month, shipped every 4 weeks. Prices are the same at every dose.

Brand-name medication is available at self-pay prices: Ozempic $1,399/month and Zepbound $1,599/month. The $49 rate is the lowest long-run price on our list, but it assumes you are comfortable committing to 12 months - check the plan terms, including cancellation, before you sign up.

Compounded GLP-1s are not FDA-approved.

Semaglutide - 12-month plan

Compounded semaglutide

$49/mo

12-month plan, rate locked (month-to-month ~$88/mo)

  • Same price at every dose
  • Board-certified clinicians
  • All 50 states

Tirzepatide

Compounded tirzepatide

$89/mo

Shipped every 4 weeks

  • Same price at every dose
  • Video or messaging follow-up
  • Ships in 3-5 business days

Brand-name shelf

Ozempic / Zepbound

$1,399+/mo

Self-pay prices

  • Ozempic $1,399/mo
  • Zepbound $1,599/mo

What we like about wellmedr

  • Lowest long-run price we found - semaglutide $49/month on the 12-month plan
  • Tirzepatide at $89/month, and prices do not rise with your dose
  • Strongest published Trustpilot score on our list (4.6 / 5 from 2,181 reviews)
  • Board-certified clinicians, available in all 50 states

Worth keeping in mind

  • The $49 price requires a 12-month commitment; month-to-month is around $88/month
  • Compounded medication is not FDA-approved or FDA-reviewed for safety, effectiveness or quality
  • Slower shipping than embody or trimrx - 3-5 business days
  • A broad multi-category platform rather than a weight-loss specialist

What real wellmedr customers are saying

wellmedr logo

wellmedr reviews on

Trustpilot
(2,181 reviews)
Oct 11, 2026

The experience is wonderful.

“The experience is wonderful. Their's so many companies this one is by far the best they make it so convenient for you to receive your order I've had no problems at all.”

M

Missymoo

US

Oct 10, 2026

I have had such a great Customer...

“I have had such a great Customer Service experience with Wellmdr. Ryan was awesome and helped me in every way possible. I accidentally threw away the vials when I received the order and he helped me come up with a solution to my problem. I'm very pleased with this company and excited to start taking the medication. 10 out of 10 recommendation. Thank you Wellmedr.”

K

Kari Hensley Hall

US

Oct 11, 2026

Great customer service and affordable...

“Great customer service and affordable program. Everything is going really well. I can recommend WellMedr 🙂”

M

Michael D.

US

Oct 10, 2026

I had a wonderful Customer service rep...

“I had a wonderful Customer service rep named Lana.she fixed every question I had and made the experience so easy. I was so grateful that all went well. Lana was so knowledgeable and caring. She should definitely get a raise.”

A

Ann Ward

US

Customer Service

“Paige helped me quickly by changing a delivery date. Very fast and kind service.”

g

gwenn devereaux

US

Oct 10, 2026

Michael John was very kind and patient...

“Michael John was very kind and patient with me. He answered all of my questions and did not rush me! He made me feel very comfortable”

K

Kelly

US

Oct 10, 2026

Honestly I’ve had a good experience

“Honestly I’ve had a good experience, i ordered Oct 1 got my shipment October 7th, customer service replies to me, they even moved my payment date to better accommodate my income and pay days!! I can’t thank them enough for that. I’m a single mom from Ohio, my doctors said this can help my false brain tumor symptoms plus I need to lose some weight so I’m grateful for this company making it affordable even for people on a fixed income.”

S

Savannah James

US

“Ashton Jone was extremely helpful !”

N

N/A

US

Oct 10, 2026

Dylan answered all my questions quickly...

“Dylan answered all my questions quickly and professionally”

G

Gail Rosencranz

US

Oct 10, 2026

My experience with Brittany was great...

“My experience with Brittany was great and she was professional and helpful, I left the program because my first order was messed up and I had to reach out several times to get an answer, I’m just worried if month 1 was so late, is it always going to be? But the resolution was flawless thanks to Brittany”

D

Debbie

US

They resolved my problem with a nice...

“They resolved my problem with a nice attitude she was very helpful”

Y

Yesenia Valladarez

US

Get started with wellmedr

trimrx vs. wellmedr: What’s the Difference?

The key differences to consider when comparing the two providers.

trimrxwellmedr
Starting price$149/mo$49/mo on 12-month plan
MedicationsCompounded sema & tirz + brandedCompounded sema & tirz + brand-name
Semaglutide$149/mo, every dose$49/mo (12-mo) / ~$88 monthly
Tirzepatide$259/mo$89/mo
DosingCustom dosingStandard titration
Provider check-insUnlimitedAsync + video/messaging
ShippingFree, often next-day3-5 business days
Trustpilot3.8/5 (5,393)4.6/5 (2,181)

So which one should you pick?

Find the line that sounds like you - that’s your answer.

$49/mo semaglutide on the 12-month planwellmedr
$89/mo tirzepatide - $170 less than trimrxwellmedr
4.6/5 on Trustpilot from 2,181 reviewswellmedr
Custom dosing with unlimited provider check-instrimrx
Free tracked delivery, often next-daytrimrx
$149/mo semaglutide month-to-monthtrimrx

Here’s the short version

On price alone, this is not a contest: wellmedr's $49/mo semaglutide (12-month plan) and $89/mo tirzepatide sit far below trimrx's $149 and $259. So why would anyone pick trimrx?

Because it sells something wellmedr does not lead on - custom dosing and unlimited check-ins with a provider, plus delivery that often arrives the next day. For people who struggle with side effects as the dose goes up, that hands-on adjustment can be what keeps them on treatment.

The quick answer

Go with wellmedr if you want

  • $49/mo semaglutide on the 12-month plan
  • $89/mo tirzepatide - $170 less than trimrx
  • 4.6/5 on Trustpilot from 2,181 reviews

trimrx makes more sense if you want

  • Custom dosing with unlimited provider check-ins
  • Free tracked delivery, often next-day
  • $149/mo semaglutide month-to-month

Had to pick one for most people? wellmedr. The numbers and customer feedback below are why - and where trimrx wins instead.

trimrx vs wellmedr: FAQs

Which is better, trimrx vs wellmedr?

wellmedr is the better choice for most people. The same medications cost $100/mo less for semaglutide and $170/mo less for tirzepatide, and its 4.6/5 Trustpilot score (2,181 reviews) beats trimrx's 3.8 (5,393). Pick trimrx if you want custom or slower dose steps and unlimited access to a provider, if you need medication fast, or if you will not commit to a 12-month plan - trimrx's $149/mo semaglutide is month-to-month. Compounded medications are not FDA-approved, and a licensed clinician decides what is right for you.

Is trimrx cheaper than wellmedr?

wellmedr: $49/mo semaglutide on a 12-month plan (around $88 month-to-month) and $89/mo tirzepatide. trimrx: $149/mo semaglutide and $259/mo tirzepatide, month-to-month. Even wellmedr's month-to-month semaglutide is about $61 cheaper.

Which has better medical support, trimrx or wellmedr?

trimrx builds custom dosing and unlimited provider check-ins into the price - useful if you are side-effect sensitive and want smaller steps. wellmedr uses board-certified clinicians with an async intake plus video and messaging, but dosing support is not its headline.

Which is faster, trimrx or wellmedr?

trimrx offers free tracked delivery that often arrives the next day. wellmedr ships in 3-5 business days.

Which has better customer reviews, trimrx or wellmedr?

wellmedr has 4.6/5 from 2,181 Trustpilot reviews; trimrx has 3.8/5 from 5,393.

Which offers more flexible plans, trimrx or wellmedr?

trimrx is month-to-month at its listed prices. wellmedr's lowest semaglutide price requires a 12-month plan.

Sources & methodology

We built this comparison of trimrx and wellmedr from each provider'sown published pricing, plans and policies, cross-checked against regulatory and peer-reviewed medical references, and read alongside real customer feedback. Prices and plan details were verified against the provider's published information; we do not take providers' word for their own claims without checking.

Provider information

Pricing, plans, shipping and policies, checked against each provider's own site.

  • trimrx - full pricing & plan breakdown
  • wellmedr - full pricing & plan breakdown

Provider data checked September 2026

Customer & community feedback

Third-party signals shown on this page and in our full reviews: verified Trustpilot ratings, public Reddit discussions, and independent YouTube reviews. We report what these sources say - we never fold their ratings into our own scores.

Medical & regulatory references

  1. 1.FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss - U.S. Food & Drug Administration
  2. 2.FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize - U.S. Food & Drug Administration
  3. 3.Wegovy (semaglutide) injection - prescribing information - U.S. Food & Drug Administration (Drugs@FDA)
  4. 4.Zepbound (tirzepatide) injection - prescribing information - U.S. Food & Drug Administration (Drugs@FDA)
  5. 5.Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1) - Wilding et al. - New England Journal of Medicine, 2021;384:989-1002
  6. 6.Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1) - Jastreboff et al. - New England Journal of Medicine, 2022;387:205-216
  7. 7.Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5) - Aronne et al. - New England Journal of Medicine, 2025
  8. 8.Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension - Wilding et al. - Diabetes, Obesity and Metabolism, 2022
  9. 9.Prescription Medications to Treat Overweight & Obesity - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH

Last reviewed September 2026. We revisit comparisons when providers change their pricing or policies. This page is information only and is not medical advice - always consult a licensed clinician before starting treatment.